A lifesaving operation turned tragic when a Michigan girl contracted COVID-19 from her double lung transplant final 12 months and died quickly after.
The case marks the primary time that docs have confirmed COVID-19 transmission via an organ transplant, in response to a report of the case, revealed Feb. 10 within the American Journal of Transplantation.
A surgeon concerned within the girl’s case additionally contracted COVID-19, probably throughout the transplant process, the report mentioned. The surgeon later recovered, in response to Kaiser Well being Information.
On condition that that is the one confirmed case of COVID-19 unfold via organ transplantation out of practically 40,000 organ transplants carried out in 2020, transmission via this route is uncommon, Kaiser Well being Information reported. However docs concerned with the case are calling for extra in depth COVID-19 testing of lung donors to stop such transmission from taking place.
On this case, the donor, who died in a automobile accident, was unknowingly contaminated with COVID-19 and examined destructive on customary assessments of the nostril and throat. “We’d completely not have used the lungs if we would had a constructive COVID take a look at,” Dr. Daniel Kaul, director of Michigan Drugs’s transplant infectious illness service and lead writer of the report, instructed Kaiser Well being Information.
The lung transplant recipient was a girl with power obstructive lung illness (COPD). Her transplant process went easily, however simply three days after the operation, she developed a fever and respiration issues and was positioned on a ventilator. Samples from her lungs examined constructive for COVID-19.
Although customary COVID-19 assessments got here again destructive, docs discovered a pattern of fluid that had been washed via the donor’s lungs. This lung fluid pattern examined constructive for COVID-19.
Genetic sequencing revealed that the coronavirus infecting the recipient and the donor have been equivalent, confirming that the recipient contracted the virus from the donor lungs. The surgeon, who bought sick 4 days after the transplant process, was additionally contaminated with a just about equivalent virus, which he probably contracted from materials expelled from the donor lungs throughout the operation, the report mentioned.
After contracting COVID-19, the transplant recipient developed multiorgan failure and died two months later, regardless of in depth remedy, Kaiser Well being Information reported.
“Transplant facilities and organ procurement organizations ought to carry out SARS-CoV-2 testing of decrease respiratory tract specimens [from deep in the lungs] from potential lung donors,” the authors wrote of their paper. As well as, transplant facilities ought to “think about enhanced private protecting gear for well being care employees concerned in lung procurement and transplantation,” equivalent to N95 masks and eye safety, they concluded.
Initially revealed on Reside Science.